ENDOTHELIAL DYSFUNCTION AND 24 HOUR AMBULATORY BLOOD PREASSURE MONITORING IN PATIENTS WITH DIABETES

Abstract

Arterial hypertension in diabetic patients plays a main role in the earlier formation of diabetic kidney disease (DKD). Endothelial dysfunction is considered to be a process based on the development of diabetic complications. It is important to study the markers, which gives the opportunity to identify DKD in early stage. Article presented the study of 24hABPM data in patients with diabetes and its interconnection with estimated glomerular filtration rate and endothelial dysfunction. The endothelial function was determined by the levels of TGF-b1(transforming growth factor-beta1) and VCAM-1 (vascular cell adhesion molecule-1). In the our study, we obtained convincing results that complex including endothelial dysfunction and results of 24hABPM can be considered as early signs of DKD progression in patients with diabetes.