NECROBIOSIS LIPOIDICA

Abstract

Necrobiosis lipoidica is a rare inflammatory disorder, which was mainly observed on diabetic patients. The skin lesions classically described in necrobiosis lipoidica initially appear as nodules or papules well circumscribed that expand later on, becoming plaques with central atrophy. Even though many theories have been suggested regarding the etiopathogeny of this disorder, the real cause of cutaneous colagen deterioration remains unknown. The lack of understanding of the etiology makes difficult to establish an optimal manner of therapy, even thought numerous treatments have been tried.