Successful management of type 2 diabetes, obesity and urinary incontinence in a 45-year-old female patient

Ivana Mickovski; Vladimir Kojovic; Daniela Buklioska Ilievska; Radmila Milosheska

Ivana Mickovski Department of Internal Medicine, Faculty of Medical Sciences, Goce Delcev University, Stip, Republic of North Macedonia https://orcid.org/0000-0002-1548-6360
Vladimir Kojovic Department of Urology, Institute for Mother and Child Health Care, Medical School, University of Belgrade, Belgrade, Serbia https://orcid.org/0000-0002-7843-0700
Daniela Buklioska Ilievska Department of Internal Medicine, Faculty of Medical Sciences, Goce Delcev University, Stip, Republic of North Macedonia https://orcid.org/0000-0002-9292-5232
Radmila Milosheska Department of Internal Medicine, City General Hospital 8th September, Skopje, Republic of North Macedonia https://orcid.org/0000-0002-8125-6440

Keywords: type 2 diabetes mellitus, obesity, stress urinary incontinence, GLP-1 1receptor agonist, metabolic control, weight loss, artificial urinary sphincter

Abstract

This case report presents a 45-year-old female patient with uncontrolled Type 2 Diabetes Mellitus (T2DM), with obesity, and stress urinary incontinence (SUI) requiring frequent diaper use. The patients underwent a stepwise treatment approach, starting with glycemic regulation and weight reduction using GLP1 receptor agonist (GLP-1RA) combined with insulin therapy and weight reduction strategies. After achieving significant metabolic improvement and weight loss, the patient successfully underwent surgical intervention with an artificial urinary sphincter (AUS) implantation, leading to complete resolution of incontinence. This case highlights the importance of a comprehensive, multidisciplinary approach in managing complex metabolic and urological conditions.